abstract：:Administration of ethanol extract of stem bark from Z. rhoifolium (EEtOH-ZR) induced hypotension associated with a dual effect in heart rate in normotensive rats. This response was highlighted in spontaneously hypertensive rats (SHR). In rat superior mesenteric artery rings, the cumulative addition of EEtOH-ZR (0.1-75...

journal_title：Indian journal of experimental biology

authors： Ferreira-Filho ES,Arcanjo DD,Moura LH,da Silva-Filho JC,Paulino ET,Ribeiro EA,Chaves MH,Oliveira Rde C,de Oliveira AP

更新日期：2013-08-01 00:00:00

abstract：:Since aging is the most important risk factor for variety of diseases, the discovery of a wide range of chemical modulators of aging in model organisms encourages new strategies for targeting age associated diseases. Simple genetic manipulation leads to long-lived and healthy animals, so any compound which could have ...

journal_title：Indian journal of experimental biology

authors： Pandey R,Gupta S,Shukla V,Tandon S,Shukla V

更新日期：2013-07-01 00:00:00

abstract：:Leaves of P. sativum the double mutant genotype tendril-less (tl) leaflet-development (lld), due to the action of lld mutation, produce many leaflets that are aborted at different stages of development. Morphological, vein pattern and histological observations showed that aborted leaflets became cup/bell/trumpet (cup)...

journal_title：Indian journal of experimental biology

authors： Sharma V,Tripathi BN,Kumar S

更新日期：2013-06-01 00:00:00

abstract：:The high intake of refined sugars, mainly fructose has been implicated in the epidemiology of metabolic diseases in adults and children. With an aim to determine whether honey can substitute refined sugars without adverse effect, the long-term effects of natural honey and cane syrup have been compared on visceral morp...

journal_title：Indian journal of experimental biology

authors： Ajibola A,Chamunorwa JP,Erlwanger KH

更新日期：2013-04-01 00:00:00

abstract：:In the experimental group (shh inhibited group), there were significant decreases in the expression of Oct4, Nanog, Shh, GATA4, Brachyury and Goosecoid, while increases were observed for TAT and Pdx1. The expression of Sox17 did not differ between two control and experimental groups. In experimental group, the amount ...

journal_title：Indian journal of experimental biology

authors： Ghanbari A,Khazaei M,Hashemi-Tabar M,Rabzia A,Fathi F,Bayat PD

更新日期：2013-03-01 00:00:00

abstract：:In view of the contribution of iron deposition in the oxidative pathologic process of liver disease, the potential of 70% methanolic extract of C. cajan leaf (CLME) towards antioxidative protection against iron-overload-induced liver damage in mice has been investigated. DPPH radical scavenging and protection of Fento...

journal_title：Indian journal of experimental biology

authors： Sarkar R,Hazra B,Mandal N

更新日期：2013-02-01 00:00:00

abstract：:While there is an emphasis on the early glycemic control for its long-term benefits in preventing microvascular complications of diabetes, the biochemical mechanisms responsible for the long-lasting effects are not clearly understood. Therefore the impact of early insulin (EI) versus late insulin (LI) treatment on dia...

journal_title：Indian journal of experimental biology

authors： Balakumar M,Saravanan N,Prabhu D,Regin B,Reddy GB,Mohan V,Rema M,Balasubramanyam M

更新日期：2013-01-01 00:00:00

abstract：:This study was designed to check whether insulin supplementation is crucial for inducing diabetic nephropathy (DNP) in Wistar rats. Diabetes was induced by a single intraperitoneal injection of streptozotocin. The urinary biochemical parameters such as albumin, creatinine and urea nitrogen were monitored every two wee...

journal_title：Indian journal of experimental biology

authors： Michael ST,Ganesh RN,Viswanathan P

更新日期：2012-12-01 00:00:00

abstract：:The antioxidant activities of the crude hydro-alcoholic extract (CE) and its four fractions viz. methanol (MF), ethyl acetate (EF), n-Butanol (BF), and precipitated aqueous (PAF) of A.racemosus roots tested decreased in the order of EF > MF > CE > BF > PAF when investigated by DPPH free radical scavenging assay. Under...

journal_title：Indian journal of experimental biology

authors： Acharya SR,Acharya NS,Bhangale JO,Shah SK,Pandya SS

更新日期：2012-11-01 00:00:00

abstract：:Effects of ampicillin (Amp) in combination with riboflavin on septic arthritis in mice infected with Staphylococcus aureus have been reported. Ampicillin was given at 100 mg/kg after 24 h of infection, followed by riboflavin (Ribo) at 20 mg/kg body wt, after 2 h of Amp treatment. Mice were sacrificed at 3, 9, 15 days ...

journal_title：Indian journal of experimental biology

authors： Mal P,Ghosh D,Bandyopadhyay D,Dutta K,Bishayi B

更新日期：2012-10-01 00:00:00

abstract：:The present study was designed to investigate the putative antidepressant and anxiolytic-like effects of N-n-Butylquinoxalin-2-carboxamide (4n), a novel 5-HT3 receptor antagonist, with an optimal log P (2.01) and pA2 value (7.3) greater than ondansetron (6.9) using rodent behavioural models of depression and anxiety. ...

journal_title：Indian journal of experimental biology

authors： Kumar B,Jindal A,Pandey DK,Bhatt S,Devadoss T,Mahesh R

更新日期：2012-09-01 00:00:00

abstract：:Naturally fertilized Microhyla ornata and Xenopus laevis embryos at dorsal lip of blastopore stage were exposed to 0.3, and 0.6% sodium chloride for high salinity treatment and dilute hydrochloric acid and sodium hydroxide for treatment with low and high pH, respectively. After treatment for different durations, embry...

journal_title：Indian journal of experimental biology

authors： Chougule B,Asashima M,Patwardhan V,Ghaskadbi S

更新日期：2012-08-01 00:00:00

abstract：:The biodegradation of spent saline bottles, a low density polyethylene product (LDPE) by two selected Arthrobacter sp. under in vitro conditions is reported. Chemical and UV pretreatment play a vital role in enhancing the rate of biodegradation. Treated LDPE film exhibits a higher weight loss and density when compared...

journal_title：Indian journal of experimental biology

authors： Carol D,Karpagam S,Kingsley SJ,Vincent S

更新日期：2012-07-01 00:00:00

abstract：:Effects of short-term administration of corticosterone and cortisol on plasma levels of thyroid hormones, gonado-somatic index and testicular histology have been reported in catfish, Clarias gariepinus during different phases of its breeding cycle. Corticosterone administration had no significant effect on plasma leve...

journal_title：Indian journal of experimental biology

authors： Suchiang P,Varkey S,Gupta BB

更新日期：2012-06-01 00:00:00

abstract：:We have found and synthesized a trapping ligand peptide H22-LP (the conservative sequence is NAHCALL) from a random phage library according to the broad-spectrum trapping receptor H22, which derived from the residue 14-35 near the N-terminal region of receptor US28 on HCMV. In this study, we will evaluate its potentia...

journal_title：Indian journal of experimental biology

authors： Liu HA,Sun HX,Mo XM,Li SY,Li XY,Zhang G,Lu L

更新日期：2012-05-01 00:00:00

abstract：:Safety and immunogenicity of Brucella abortus RB51 vaccine has been evaluated in an organised dairy farm in India. All the cattle (r = 29) vaccinated with strain RB51 'responded' to the vaccine as demonstrated by iELISA using acetone killed strain RB51 antigen. The percentage responders at day 35, 60 and 90 post vacci...

journal_title：Indian journal of experimental biology

authors： Singh R,Basera SS,Tewari K,Yadav S,Joshi S,Singh B,Mukherjee F

更新日期：2012-03-01 00:00:00

abstract：:The Malnad region located in the Western Ghats of Karnataka is known for the cultivation of indigenous rain fed land race cultivar of rice. The present study was to investigate the callogenic and caulogenic potentialities of the two indigenous rice cultivar namely Karimundaga and Kanadatumba using dehusked mature embr...

journal_title：Indian journal of experimental biology

authors： Gnanesh AU,Krishna V,Kumar RS,Venkatesh,Kumar SR,Shashidhar HE

更新日期：2012-02-01 00:00:00

abstract：:There was a significant increase in fucose (52%), total hexoses (16%) and hexosamine (56%) except sialic acid, which was reduced (77%) in the microvillus membrane of infants born to rat mothers made diabetic by injecting alloxan on day 3 of gestation. Expressed on the protein basis there were a significant increase in...

journal_title：Indian journal of experimental biology

authors： Sharma R,Chauhan SS,Mahmood A

更新日期：2012-01-01 00:00:00

abstract：:Crayfish exoskeleton (CE) samples are generally less invasive and easy to be collected. However, it is difficult to extract DNA from them. This study was intended to investigate CE as a DNA source and design an easy and efficient DNA extraction protocol for polymerase chain reactions. Specific primer pair (PPO-F, PPO-...

journal_title：Indian journal of experimental biology

authors： Li Y,Wang W,Liu X,Luo W,Zhang J,Gul Y

更新日期：2011-12-01 00:00:00

abstract：:Dual role of TGF-beta signaling in breast tumorigenesis as an inhibitor in early stages and promoter in advanced stages has been well established and known as TGF-beta switch. However, the biological mechanisms needs to be explored. Aim of the present study was to look for the usefulness of TGF-beta as a predictive ma...

journal_title：Indian journal of experimental biology

authors： Dave H,Trivedi S,Shah M,Shukla S

更新日期：2011-11-01 00:00:00

abstract：:Spirulina platensis treatment (400 mg kg(-1) for 25 days) effectively suppressed peripheral sensitization via modulation of glial activation and improved motor coordination and restoration of functional motor activity in collagen-induced arthritic rats. Spirulina treatment also resulted in an appreciable reduction of ...

journal_title：Indian journal of experimental biology

authors： Patro N,Sharma A,Kariaya K,Patro I

更新日期：2011-10-01 00:00:00

abstract：:Thalidomide provided significant protection against tri nitro benzene sulfonic acid induced colitis. Combination therapy also reduced colonic inflammation and all the biochemical parameters (myeloperoxidase assay, malondialdehyde assay and tumor necrosis factor-alpha, estimation) were significant as compared to contro...

journal_title：Indian journal of experimental biology

authors： Prakash O,Medhi B,Saikia UN,Pandhi P

更新日期：2011-09-01 00:00:00

abstract：:N-Cyclohexyl-3-methoxyquinoxalin-2-carboxamide (QCM-13), a novel 5-HT3 antagonist identified from a series of compounds with higher pA2 (7.6) and good log P (2.91) value was screened in rodent models of depression such as forced swim test (FST), tail suspension test (TST), interaction studies with standard anti-depres...

journal_title：Indian journal of experimental biology

authors： Gupta D,Devadoss T,Bhatt S,Gautam B,Jindal A,Pandey D,Mahesh R

更新日期：2011-08-01 00:00:00

abstract：:In presence of 7.5 microM of curcumin, no embryos or larva of zebrafish survived 3 days of incubation; however, coincubation with 144 microg/ml silymarin increased the survival rates of curcumin-treated embryos and larvae to about 70%. Moreover, in presence of 12.5 microM curcumin, all embryos died after 2 days of inc...

journal_title：Indian journal of experimental biology

authors： Shiau RJ,Shih PC,Wen YD

更新日期：2011-07-01 00:00:00

abstract：:Breast cancer is a common malignancy in women all over the world and novel therapeutic approaches are required for the treatment of patients who become refractory to conventional therapies. Thyroid cancer is being treated successfully with radioiodine since many years. The iodide is transported inside the thyroid epit...

journal_title：Indian journal of experimental biology

authors： Damle AA,Narkar AA,Badwe RA

更新日期：2011-06-01 00:00:00

abstract：:Under general anesthesia and sterile conditions, incision wound was induced in the hard palate mucosa of adult male mice. The wounds of groups 1 and 2 were irradiated daily with He-Ne laser at 3 and 7.5 J/cm2 for 120 and 300 s, respectively, while the incision wound of group 3 not exposed served as controls. On day 3 ...

journal_title：Indian journal of experimental biology

authors： Fahimipour F,Nouruzian M,Anvari M,Tafti MA,Yazdi M,Khosravi M,Dehghannayeri Z,Sabounchi SS,Bayat M

更新日期：2011-05-01 00:00:00

abstract：:Perment, a polyherbal Ayurvedic formulation that contains equal parts of Clitoria ternatea Linn., Withania somnifera Dun., Asparagus racemosus Linn., Bacopa monniera Linn., is used clinically as mood elevators. The aim of the present study was to explore the behavioural effects and to understand possible mode of actio...

journal_title：Indian journal of experimental biology

authors： Ramanathan M,Balaji B,Justin A

更新日期：2011-04-01 00:00:00

abstract：:Reperfusion injury is remarkable clinical issue that needs to be resolved as ischemia-reperfusion is a common phenomenon encountered in numerous clinical situations. The present communication report the involvement of nitric oxide (NO) in cardioprotection offered by flavonoids (rutin and quercetin) against myocardial ...

journal_title：Indian journal of experimental biology

authors： Challa SR,Akula A,Metla S,Gopal PN

更新日期：2011-03-01 00:00:00

abstract：:The p38 mitogen activated protein kinase (p38MAPK) pathway is an important signaling cascade involved in cell growth, differentiation and apoptosis. High glucose activates p38MAPK pathway in different cells, including osteoblasts. In the present study, role of p38MAPK in high glucose induced osteoblast apoptosis and p...

journal_title：Indian journal of experimental biology

authors： Feng Z,Deng H,Du J,Chen D,Jiang R,Liang X

更新日期：2011-02-01 00:00:00

abstract：:Blood samples of malaria patients (n = 30), selected based on the severity of parasitemia, were divided into low (LP), medium (MP) and high (HP) parasitemia, which represent increasing levels of the disease severity. Healthy subjects (n = 10) without any history of disease were selected as a control group. By processi...

journal_title：Indian journal of experimental biology

authors： Edison M,Jeeva JB,Singh M

更新日期：2011-01-01 00:00:00

abstract：:Cisplatin-based chemotherapy has a variety of vascular side effects. The aim of the present study was to evaluate the beneficial effect of melatonin and cisplatin on the alterations in vascular reactivity and structure of cisplatin-treated rats. Phenylephrine (PHE) and KCl-caused concentration-dependent contractions o...

journal_title：Indian journal of experimental biology

authors： Atalik KE,Keleş B,Uyar Y,Dündar MA,Oz M,Esen HH

更新日期：2010-12-01 00:00:00

abstract：:Mechanisms of interleukin-18 (IL-18) and interleukin-10 (IL-10) in lipopolysaccharide (LPS) induced endotoxemia are not clear; their protective role is being investigated so that they may effectively modulate the host cytokine levels during endotoxemia. The aim of the study was to evaluate protective effects of IL-18 ...

journal_title：Indian journal of experimental biology

authors： Nandi D,Mishra MK,Basu A,Bishayi B

更新日期：2010-11-01 00:00:00

abstract：:Chronic (2 h/d x 8 weeks) exposure to magnetic field (MF; 50 Hz, 17.9 microT) in complete spinal cord (T13) transected rats restored food intake (FI), water intake (WI) and body weight (BW) which were decreased in the spinal cord injured rats. The results suggest a significant beneficial effect of chronic exposure to ...

journal_title：Indian journal of experimental biology

authors： Kumar S,Jain S,Behari J,Avelev VD,Mathur R

更新日期：2010-10-01 00:00:00

abstract：:To evaluate the cardioprotective potential of Inula racemosa in myocardial ischemic-reperfusion injury, Wistar male albino rats were randomly divided into four groups. The group I and II animals were administered saline orally {(sham, ischemia- reperfusion (I-R) control group)} and animals of group III and group IV re...

journal_title：Indian journal of experimental biology

authors： Ojha S,Nandave M,Kumaria S,Arya DS

更新日期：2010-09-01 00:00:00

abstract：:Antinociceptive activity of methanolic extract of leaves of A. aspera was studied by peripheral/non-narcotic model of nociception like acetic acid induced writhing syndrome test and central/narcotic models like hot plate and tail flick tests. The methanolic extract of the plant, administered orally (@ 300, 600 and 900...

journal_title：Indian journal of experimental biology

authors： Barua CC,Talukdar A,Begum SA,Lahon LC,Sarma DK,Pathak DC,Borah P

更新日期：2010-08-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC), a common malignancy that possibly involves a combination of exposure to the carcinogens and inherited genetic differences in the enzymes catalyzing their metabolism. Alcohol and tobacco consumption are the primary environmental risk factors, while polymorphism in various ...

journal_title：Indian journal of experimental biology

authors： Ruwali M,Parmar D

更新日期：2010-07-01 00:00:00

abstract：:The present experiment was planned to study nephrotoxicity in experimental diabetic rats under sub-chronic exposure to arsenic. Alloxan induced diabetic and control rats were exposed to sodium arsenite (0 and 5.5 mg/kg, orally) for 30 days. More pronounced nephrotoxic effects were noted in arsenic exposed diabetic gro...

journal_title：Indian journal of experimental biology

authors： Patel HV,Kalia K

更新日期：2010-07-01 00:00:00

abstract：:Cyclooxygenase (COX) isoenzyme is known to play an important role in the pathophysiology of Parkinson's disease. The present study evaluated the neuroprotective effect of nimesulide, a preferential COX-2-inhibitor against 1-methyl-4-phenyl-1,2,3,6-tertahydropyridine (MPTP)-model of Parkinson's disease. Intrastriatal a...

journal_title：Indian journal of experimental biology

authors： Gupta A,Dhir A,Kumar A,Kulkarni SK

更新日期：2010-06-01 00:00:00

abstract：:Melanoma antigen-encoding gene 3 (MAGE-3) is an ideal candidate for a tumor vaccine although its potency need to be increased. Heat shock proteins (HSPs) represents a potential approach for increasing the potency of DNA vaccines. In the present study, a fusion DNA vaccine composed of Mycobacterium tuberculosis HSP70 a...

journal_title：Indian journal of experimental biology

authors： Qu P,Ma JH,Zhang XM,Huang XJ,Yang XW,Yan-Fang S

更新日期：2010-05-01 00:00:00

abstract：:Fissioncytorace-1, a member of the nasuta-albomicans complex of Drosophila is an evolutionary product of centric fission, which had occurred in the chromosome X3 of Cytorace 1, a hydridization product of Drosophila nasuta nasuta male (2n=8) and Drosophila nasuta albomicans female (2n=6). Cytorace 1 (males 2n=7; female...

journal_title：Indian journal of experimental biology

authors： Bijaya T,Ramachandra NB

更新日期：2010-05-01 00:00:00